## Description

This track shows the alignment of a complete Neandertal mitochondrial sequence to a modern human mitochondrial sequence.

Note: the mitochondrion used as the genome browser reference sequence "chrM" in hg18 and hg19 is NC_001807, which has been deprecated. Future human genome browsers will use the revised Cambridge Reference Sequence (rCRS) NC_012920.

## Display Conventions and Configuration

This track follows the display conventions for PSL alignment tracks. Mismatching bases are highlighted as described here. Several types of alignment gap may also be colored; for more information, click here.

## Methods

DNA was extracted from a 38,000-year-old bone and sequenced using methods described in Green, et al. The Neandertal mitochondrial sequence (NC_011137) was downloaded from GenBank and aligned to chrM (NC_001807) using BLAT.

## Reference

Green RE, Malaspinas AS, Krause J, Briggs AW, Johnson PL, Uhler C, Meyer M, Good JM, Maricic T, Stenzel U et al. A complete Neandertal mitochondrial genome sequence determined by high-throughput sequencing. Cell. 2008 Aug 8;134(3):416-26.